Vaccine History

Name:

Date:

Instructions: Learn about the vaccines that changed the world and the scientists behind them

1.
Who developed the first successful vaccine, against smallpox, in 1796?
A
Robert Koch
B
Joseph Lister
C
Louis Pasteur
D
Edward Jenner
2.
Edward Jenner's smallpox vaccine was derived from which related, milder disease?
A
Cowpox
B
Influenza
C
Chickenpox
D
Measles
3.
Which scientist developed the first rabies vaccine in 1885?
A
Paul Ehrlich
B
Louis Pasteur
C
Alexander Fleming
D
Robert Koch
4.
Jonas Salk developed a vaccine in 1955 that helped eradicate which crippling disease?
A
Diphtheria
B
Polio
C
Tuberculosis
D
Typhoid
5.
What type of vaccine uses a weakened form of the virus to build immunity?
A
Toxoid vaccine
B
Subunit vaccine
C
Live attenuated vaccine
D
Inactivated vaccine
6.
Smallpox was declared officially eradicated by the World Health Organization in what year?
A
1975
B
1980
C
1970
D
1985
7.
What does the MMR vaccine protect against?
A
Measles, Mumps, Rubella
B
Malaria, Meningitis, Rabies
C
Mono, Mumps, Rotavirus
D
Meningitis, Measles, Rickets
8.
Albert Sabin developed an oral version of which vaccine in the late 1950s?
A
Smallpox
B
Tuberculosis
C
Yellow fever
D
Polio
9.
What new technology was used in the Pfizer-BioNTech and Moderna COVID-19 vaccines?
A
mRNA
B
Bacterial vector
C
Inactivated virus
D
Live virus
10.
The BCG vaccine, widely used around the world, protects against which disease?
A
Hepatitis B
B
Yellow fever
C
Cholera
D
Tuberculosis
11.
What is herd immunity?
A
When enough people are immune that disease spread is limited
B
A type of vaccine for livestock
C
Immunity only in animals
D
Natural immunity from exposure
12.
Which childhood disease, once a leading cause of death, was the first to be targeted by a global vaccination campaign?
A
Polio
B
Diphtheria
C
Measles
D
Smallpox
13.
What organization leads global vaccination efforts and declared smallpox eradicated?
A
Red Cross
B
Centers for Disease Control
C
World Health Organization
D
UNICEF
14.
The flu vaccine must be updated each year because influenza viruses do what frequently?
A
Mutate
B
Grow larger
C
Become dormant
D
Become extinct
15.
What is the term for the process of testing a vaccine's safety and effectiveness before public use?
A
Field survey
B
Clinical trials
C
Peer review
D
Laboratory analysis

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