Vaccine History
1 / 15Learn about the vaccines that changed the world and the scientists behind them
15 quick questionsNo sign-upFree to playTap an answer below to begin ↓
Who developed the first successful vaccine, against smallpox, in 1796?
About Vaccine History
Learn about the vaccines that changed the world and the scientists behind them Vaccine History packs 15 multiple-choice questions aimed at mixed difficulty into a relaxed session of roughly 7 minutes — no sign-up, no timer pressure. An explanation appears after every answer, and finishing once a day keeps your streak alive.
A few sample questions
1. Who developed the first successful vaccine, against smallpox, in 1796?
Answer: Edward Jenner
2. Edward Jenner's smallpox vaccine was derived from which related, milder disease?
Answer: Cowpox
3. Which scientist developed the first rabies vaccine in 1885?
Answer: Louis Pasteur
4. Jonas Salk developed a vaccine in 1955 that helped eradicate which crippling disease?
Answer: Polio
5. What type of vaccine uses a weakened form of the virus to build immunity?
Answer: Live attenuated vaccine
Frequently asked questions
Can I print Vaccine History?
Yes — use the Print button at the top of the page for a clean question sheet, or "Print with Answers" to make an answer key. Printed sheets work well for group play at home, in a classroom, or at a senior center.
Will I lose my progress if I close the page?
Your overall progress — XP, streaks, and badges — is saved in your browser automatically. A quiz that's underway restarts if you leave mid-game, but at about 7 minutes, Vaccine History fits comfortably in one sitting.
How many questions are in Vaccine History?
Vaccine History has 15 multiple-choice questions. Each one has four answer options and an explanation that appears after you answer, so you learn something even when you miss.
Is Vaccine History free to play?
Yes. The entire SeniorBrainGames catalog — including Vaccine History — is free, with no sign-up required, no time limits, and no ads on top of the game. It also works offline once the page has loaded once.
Explore related topics
More General Knowledge
Chocolate History & Science
Discover the sweet history and science behind chocolate!
Inventions That Changed History
Groundbreaking inventions and their inventors
Famous Shipwrecks of History
From the Titanic to ancient Bronze Age cargo ships, discover the dramatic true stories behind history's most memorable losses at sea.
Famous Women in History
How well do you know the women who changed the world?
American History Highlights
Journey through key moments in American history, from the Revolution to the Space Age.
Try Memory Games
The Verdict Is In: Famous Trials Through History
From the Scopes Monkey Trial to the Nuremberg Tribunals, the courtrooms of history have witnessed some of the most dramatic — and consequential — moments of the 20th century. How well do you know the verdicts, the attorneys, and the stories behind them?
Try Memory Games
Roll the Dice: Classic Board Game History Quiz
Monopoly, Scrabble, Clue — these beloved games have fascinating origin stories that are just as fun as the games themselves. Test your knowledge of the inventors, companies, and surprising facts behind America's favorite board games.
From our guides
Daily Brain Training for Older Adults
Build a simple daily routine that keeps your mind active.